Wound care research papers

TransCyte (Advanced Tissue Sciences Inc. La Jolla, CA), a bioactive skin substitute, was granted premarket approval (PMA) by the FDA in 1997 for "for use as a temporary wound covering for surgically excised full-thickness and deep partial-thickness thermal burn wounds in patients who require such a covering prior to autograft placement." TranCyte was not indicated for chronic wounds.  TransCyte consists of human dermal fibroblasts grown on nylon mesh, combined with a synthetic epidermal layer.  TransCyte can be used as a temporary covering over full thickness and some partial-thickness burns until autografting is possible.  It can also be used as a temporary covering for some burn wounds that heal without autografting.  TransCyte is packaged and shipped in a cryo-preserved state to burn treatment centers.  The surgeon then thaws the product and stretches it over a burn site.  In about 7 to 14 days, the TransCyte starts peeling off, and the surgeon trims it away as it peels.

Wound care research papers

wound care research papers

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